How does liver cirrhosis contribute to the development of ascites?

Master the EDAPT Altered Hepatobiliary Function Exam. Explore flashcards and comprehensive questions, each with insights and explanations. Get ready for success!

Liver cirrhosis is a condition characterized by progressive scarring and damage to the liver, which ultimately affects its ability to function properly. One of the key complications of cirrhosis is the development of ascites, which is the accumulation of fluid in the abdominal cavity.

The correct answer highlights two critical factors in this process: portal hypertension and decreased albumin production. Cirrhosis leads to the development of portal hypertension due to increased resistance to blood flow through the liver caused by the fibrotic tissue that replaces normal liver cells. As blood flow becomes obstructed, pressure builds up in the portal venous system, leading to increased hydrostatic pressure in the blood vessels. This elevation in pressure drives fluid out of the vascular space and into the abdominal cavity, contributing to ascites.

Additionally, cirrhosis results in the liver's diminished ability to produce important proteins, including albumin. Albumin is crucial for maintaining oncotic pressure, which helps keep fluid within the vascular compartment. A reduction in albumin levels means there is less oncotic pressure to counteract the hydrostatic pressure, further promoting fluid leakage into the abdominal cavity.

In summary, the combination of portal hypertension and decreased albumin production creates an environment that favors

Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy