What does cholestasis refer to?

Cholestasis refers to the condition where there is a stoppage or reduction in the flow of bile from the liver. Bile, which is essential for digestion and the absorption of fats, flows from the liver through bile ducts into the small intestine. When cholestasis occurs, this flow is obstructed, leading to a buildup of bile acids in the liver and bloodstream. Consequently, this can result in various symptoms such as jaundice (yellowing of the skin and eyes), itching, and potential liver damage if the condition is prolonged.

Understanding cholestasis is critical in the context of hepatobiliary function, as it pertains to liver health and the effective functioning of bile production and secretion. Conditions that can cause cholestasis include liver diseases, bile duct obstructions, or certain metabolic disorders, highlighting the importance of recognizing this medical phenomenon.