What is typically one of the first indicators of liver dysfunction in laboratory tests?

One of the first indicators of liver dysfunction in laboratory tests is increased liver enzymes. When the liver experiences damage or stress, it releases certain enzymes into the bloodstream. Commonly measured liver enzymes include alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Elevated levels of these enzymes are indicative of acute liver injury or inflammation, as they reflect hepatocyte damage.

Monitoring liver enzyme levels is crucial not only for diagnosing liver conditions but also for gauging the severity of liver impairment. Additionally, this increase is often one of the first abnormal lab findings noted in patients with liver disease, making it a critical parameter in the assessment of liver function. Other laboratory tests may follow to provide a more comprehensive picture of liver health, but elevated liver enzymes are a key initial sign.