What laboratory values would suggest hepatobiliary dysfunction?

Alkaline phosphatase (ALP) is an important enzyme primarily found in the liver, bile ducts, and bones. Elevated levels of ALP in the blood can indicate cholestasis or bile duct obstruction, both of which are indicative of hepatobiliary dysfunction. Conditions such as liver disease, gallstones, or tumors that affect the bile ducts can lead to an increase in ALP levels. Monitoring ALP values can therefore provide critical information about the health of the hepatobiliary system.

In contrast, while the other laboratory values listed can be influenced by various conditions, they are not specific indicators of hepatobiliary dysfunction. Serum creatinine primarily assesses kidney function rather than liver function. Blood glucose levels are indicative of metabolic and endocrine functions, and hemoglobin levels are associated with blood status and not directly with liver or bile duct health.